NPC Lorain of Cruma tower is missing, she need for quests.
She's been bugged since GoD (as are all the NPC's for that quest) went live on these servers, I guess NCWest is not interested in getting them fixed.
After yesterday's maintenance, Lorain dissapeared again. You can target her, but you can't talk to her, hence making those lvl 40 quests uncompletable.